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    AnesthesiaZone.com provides anesthesiologists and certified registered nurse anesthetists (CRNAs) with the latest anesthesia news and information. Keeping abreast of the latest technology, research and other medical news in the field of anesthesiology is crucial to your success, so we provide articles from leading medical journals and publications, including Anesthesia & Analgesia, Critical Care, Anesthesiology, Journal of Clinical Anesthesia and many more. To read a story in its entirety, please click on the hyperlink provided.

    Feature Article by AnesthesiaZone.com


    Research Reveals New Link Between Morphine Tolerance and Increased Sensitivity to Pain
    By Jennifer Huddleston, staff writer    A recent study conducted by researchers at the Leiden University Medical Center in Leiden, Netherlands, and the City University of New York (CUNY) in New York City, found that a metabolite of morphine called....

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    Low Dose Intravenous Midazolam For Prevention Of PONV In Lower Abdominal Surgery - Preoperative vs Intraoperative Administration
    Safavi MR et al. - The results indicated that midazolam 35 microg/kg (2 mg) given intravenously 30 minutes before the end of surgery was more effective in decreasing the incidence of PONV than midazolam premedication 35 microg/kg....
    Middle East Journal of Anesthesiology, 07/01/2009

    New Pain Guideline for Older Patients
    Kuehn BM - Physicians treating patients aged 75 years or older for chronic pain should avoid using nonsteroidal anti-inflammatory drugs (NSAIDs). The new recommendation reflects evidence about serious cardiovascular and gastrointestinal tract risks associated with this class of drugs that has emerged since 2002. These drugs also may complicate the treatment of common conditions in this population, such as hypertension and congestive heart failure....
    JAMA, 07/01/2009

    Reversal of refractory septic shock with drotrecogin alpha (activated)
    Vieillard-Baron A et al. - The objective of this study was to investigate whether early administration of drotrecogin alpha (activated) (DrotAA) to this selected subgroup of septic patients at extremely high risk of death would significantly improve prognosis. DrotAA therapy was associated with unexpectedly high 28-day survival in patients with "refractory" septic shock....
    Intensive Care Medicine, 07/01/2009

    Prone positioning for ARDS following blunt chest trauma in late pregnancy
    Kenn S et al. - Prone positioning can be used safely and effectively in a pregnant patient. It might be superior to other therapeutic options for improvement of oxygenation in pregnant patients. Careful positioning avoiding any external abdominal pressure and continuous fetal monitoring are mandatory....
    International Journal of Obstetric Anesthesia , 07/01/2009

    Metformin-associated lactic acidosis: A prognostic and therapeutic study
    Seidowsky A et al. - The outcome of MALA was uniformly favorable after intentional metformin overdose. The vital prognosis was mainly influenced by the occurrence of multiple organ dysfunctions, the best predictive factor of death being an acute liver dysfunction as assessed by PT activity. Prolonged HD was needed to correct metformin overdose....
    Critical Care Medicine, 07/01/2009

    Risk Factors for Neurological Deficiency One Year after Blunt-Induced Traumatic Cervical Fracture
    Pull ter Gunne AF et al. - During patient evaluation, the identified variables should be taken into account. If one understands the risk factors, then it is possible to explain the expected outcome after the spine fracture....
    European Neurology, 07/01/2009

    Estimation of Optimal CPR Chest Compression Depth in Children by Using Computer Tomography
    Braga MS et al. - By using CT reconstruction estimates of chest dimensions across the developmental spectrum from 0 to 8 years of age, authors demonstrated that a simulated CC targeting approximately one-third external AP chest depth seems radiographically appropriate for children aged 3 months to 8 years, whereas simulated CC targeting approximately one-half external AP chest depth seems radiographically to be too deep, resulting in residual internal chest depth of <10 mm for most patients of this age....
    Pediatrics, 07/01/2009

    Intensive care of aneurysmal subarachnoid hemorrhage: an international survey
    Stevens RD et al. - Patients with aneurysmal subarachnoid hemorrhage (SAH) are routinely admitted to the intensive care unit for the management of neurological and systemic complications. This study demonstrates that the practices of intensive care physicians treating SAH are heterogeneous and often at variance with available evidence....
    Intensive Care Medicine, 07/01/2009

    The impact of body position on intra-abdominal pressure measurement: A multicenter analysis
    Widder S et al. - Head of bed elevation results in clinically significant increases in measured IAP. Consistent body positioning from one IAP measurement to the next is necessary to allow consistent trending of IAP for accurate clinical decision making. Studies that involve IAP measurements should describe the patient's body position so that these values may be properly interpreted....
    Critical Care Medicine, 07/01/2009

    Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: a multicentre randomised controlled trial
    Jabre P et al. - The results show that ketamine is a safe and valuable alternative to etomidate for endotracheal intubation in critically ill patients, and should be considered in those with sepsis....
    The Lancet - Early Online Publication, 07/01/2009

    Subcutaneous Peripheral Nerve Stimulation With Paddle Lead for Treatment of Low Back Pain: Case Report
    Ordia J et al. - Peripheral nerve stimulation has become a useful tool in neuromodulation in the treatment of chronic and intractable pain syndromes. This case had excellent stimulation and reduction of his pain after the device was replaced with an insulated subcutaneous paddle lead....
    Neuromodulation, 07/01/2009

    Successful Treatment of Chronic Neuropathic Pain With Subcutaneous Peripheral Nerve Stimulation: Four Case Reports
    Tamimi MA et al. - The use of subcutaneous peripheral nerve stimulation as a viable treatment alternative in certain cases of chronic neuropathic pain should continue to be rigorously evaluated....
    Neuromodulation, 07/01/2009

    Anaesthetic management of a pregnant woman with carcinoid disease
    Woo KM et al. - The anaesthetic management of a 29-year-old parturient with metastatic carcinoid tumour is presented. Although the patient did not ultimately develop carcinoid syndrome during the peripartum period, it was important that a multidisciplinary team approach, with close monitoring of her antenatal progress, and planned epidural analgesia for labour and delivery is used....
    International Journal of Obstetric Anesthesia , 07/01/2009

    Spinal anesthesia for a cesarean delivery in a woman with type-2M von Willebrand disease: case report and mini-review
    Cata JP et al. - A 38-year-old multiparous woman who presented at 36 weeks’ of gestation with spontaneous rupture of membranes for urgent cesarean delivery is reported. Preoperative coagulation tests were normal except for prolonged platelet adhesion and aggregation tests. The cesarean delivery was performed under spinal anesthesia with hyperbaric bupivacaine, fentanyl and morphine sulfate....
    International Journal of Obstetric Anesthesia , 07/01/2009

    Written information that relatives of adult intensive care unit patients would like to receive- A comparison to published recommendations and opinion of staff members
    Soltner C et al. - Opinions of relatives should be taken into account when designing ICU information booklets. Relatives want more information than that anticipated by physicians or suggested in guidelines, but the youngest or the less-educated ones may respond less favorably to written information....
    Critical Care Medicine, 07/01/2009

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